Published Research

A selection of papers from our research is listed below:

  • Olckers A., DNA evidence in South Africa: Lessons Learned. Forensic Science International: Genetics Supplement series, 4, e160-e161, 2013.
  • Olckers A., Blumenthal R. and Greyling A. Forensic Science in South Africa: Status of the Profession. Forensic Science International: Genetics Supplement series, 4, e146-e147, 2013.
  • Vd Merwe A., Greyling A. and Olckers A. Training of legal professionals in DNA evidence. Forensic Science International: Genetics Supplement series, 4, e85-e86, 2013.    –
  • Drögemöller B.I., Plummer M., Korkie L., Agenbag G., Dunaiski A., Niehaus D., Koen L., Gebhardt S., Schneider N., Olckers A., Wright G., Warnich L. Characterization of the genetic variation present in CYP3A4 in three South African populations. Frontiers in Genetics: Pharmacogenetics and Pharmacogenomics, 4, article 17, p1-11, 2013.
  • Olckers A., Van der Merwe A., Towers G.W., Retief C.F., Honey E. and Schutte C.M. Compound heterozygosity in a South African patient with Facioscapulohumeral muscular dystrophy. Neuromuscular Disorders, 22, 728-734, 2012. (impact factor 2.797)
  • Schutte A., Schutte R., Huisman H.W., Van Rooyen J., Malan L., Olckers A. and Malan N. Classifying Africans with the Metabolic Syndrome. Hormone and Metabolic Research, 41, 79-85, 2009.  (impact factor 2.254)
  • Schwarz P.E.H., Towers G.W., vd Merwe A., Perez‑Perez L., Rheeder P., Schulze J.,  Bornstein S.R., Licinio J, Wong M.-L., Schutte A.E. and Olckers A. Global meta-analysis of the C-11377G alteration in the ADIPOQ gene indicates the presence of population specific effects – challenge for global health initiatives. The Pharmacogenomics Journal, 9, 42-48, 2009.(impact factor 4.968)
  • Van Rooyen J.M., Pretorius P.J., Britz M., Huisman H.W., Schutte A.E., Towers G.W., Olckers A., Schwarz P.E.H., Malan N.T., Malan L. and Schutte R. Genetic polymorphisms of b2 – and b3 -adrenergic receptor genes associated with characteristics of the metabolic syndrome in black South African women. Experimental and Clinical Endocrinology and Diabetes, 116 (4), p236-240, 2008.(impact factor 1.356)
  • Schutte A.E. and Olckers A. Metabolic Syndrome Risk in Black South African Women Compared to Caucasian Women. Hormone and Metabolic Research, 39 (9), p651-657, 2007.(impact factor 1.997)
  • Olckers A., Towers G.W., Vd Merwe A., Schwarz P.E.H., Rheeder P. and Schutte A.E. Protective effect against type 2 diabetes identified within the ACDC gene, in a black South African diabetic cohort. Metabolism: Clinical and Experimental, 56, 587-592, 2007. (impact factor 2.013)
  • Reinecke F., Levanets O., Olivier Y., Louw R., Semete B., Grobler A., Hidalgo J., Smeitink J.A.M., Olckers A. and Vd Westhuizen FH. Metallothionein-2A expression is inducible and protects against ROS-mediated cell death in rotenone treated HeLa cells, Bioch.J., 395, 405-415, 2006.(impact factor 4.326)
  • Mishmar D., Ruiz-Pesini E., Golik P., Macaulay V., Clark A.G., Hosseini S., Brandon M., Easley K., Chen E., Brown M.D., Sukernik R.I., Olckers A. and Wallace D.C. Natural selection shaped regional mitochondrial DNA variation in humans, Proc.Natl.Acad.Sc., 100 (1), p171-176, 2003.(impact factor 10.260)
  • Goosen C., Theron J., Ntsala M., Maree F.F., Olckers A., Botha S.V.J., Fierens C. and Vd Merwe S.W. Evaluation of a novel hemi-nested PCR assay based on the phosphoglucosamine mutase gene for detection of helicobacter pylori in saliva and dental plaque, Journal of Clinical Microbiology, 40 (1), p205-209, 2002. (impact factor 3.579)
  • Cruciani F., Santolamazza P., Shen P., Moral P., Olckers A., Modiano D., Destro-Bisol G., Holmes S., Coia V., Wallace D.C., Oefner P.J., Torroni A., Cavalli-Sforza L.L., Scozzari R. and A. Underhill P.A. An Asia to sub-Saharan Africa back migration is supported by high-resolution analysis of human Y chromosome haplotypes, American Journal of Human Genetics, 70 (5), p1197-1214, 2002. (impact factor 10.869)

A selection of peer reviewed published abstracts from our research is listed below:

  • Towers GW, Vd Merwe A, Schutte A, Rheeder P and Olckers A. Case-control analysis of specific SNPs in the ACDC gene indicate a protective effect against type 2 diabetes in black South Africans. Diabetes Medicine, 23, p 75, 2006. (impact factor 2.235)
  • Kotzé E, Vd Merwe A, Towers GW, Dalton D-L and Olckers A. Evaluation of HbA1c values and glucose curve shapes in the black South African population. Diabetes Medicine, 23, p 388, 2006. (impact factor 2.235)
  • Kotzé E, Vd Merwe A, Mataboge T, Nkadimeng K, Dalton D-L, Towers GW and Olckers A.  Optimising blood sample quality: limiting haemolyses during a 5 point OGTT. Diabetes Medicine, 23, p 263, 2006. (impact factor 2.235)
  • Mdluli L, Nkadimeng K, Kotzé E, Mataboge T, Towers GW, Alessandrini M, Vd Merwe A and Olckers A.  The PRIMER study: quality of data collected via questionnaires. Diabetes Medicine, 23, p 602, 2006. (impact factor 2.235)
  • Olckers A, Kotzé E, Towers GW and Vd Merwe A.  PRIMER: the Profiles of Resistance to Insulin in Multiple Ethnicities and Regions study. Diabetes Medicine, 23, p 56, 2006. (impact factor 2.235)
  • Perez-Perez L, Alvarez A, Towers W, Olckers A, Gehrisch S, Jaross W, Borstein S and Schwarz P. The CAPN10 122/122 (43/56/63) haplotype combination is associated with type 2 diabetes risk in a Cuban population group. Diabetes Medicine, 23, p 73, 2006. (impact factor 2.235)
  • Vd Merwe A, Towers GW, Schwarz PEH, Perez-Perez L, Schutte A, Rheeder P and Olckers A.  Population specific effects of the C-11377G alteration in the ACDC gene: meta‑analysis of the black South African, Cuban and German populations. Diabetes Medicine, 23, p 75, 2006. (impact factor 2.235)
  • Towers GW, Olckers A, Vd Merwe A and Schwarz PEH. Low frequencies of Caucasoid ‘at risk’ haplotypes within the black Southern African diabetic population alludes to possible population-specific effects. Diabetes and Metabolism, S1, p 42, 2005. (impact factor 1.100)
  • Schwarz PEH, Towers GW, Fücker K, Grässler J, Fischer S, Kurktschiev TT, Schulze J, Olckers A, Bornstein SR, Hanefeld M and Vasseur F. APM1 gene haplotypes are linked to pre-existing hypoadiponectinaemia, and through this, to the progression of Type 2 diabetes. Diabetes and Metabolism, S1, p 39, 2005. (impact factor 1.100)
  • Schutte AE, Van Rooyen JM, Huisman HW, Malan NT, Olckers A, Schwarz P. The relationship between fasting insulin and blood pressure with increasing age. Cardiovascular Journal of South Africa, 16(2), S21, 2005. (impact factor 0.780)
  • Olckers A and Van der Merwe A. Possible epigenetic protective factor for FSHD identified in the Black South African population. American Journal of Human Genetics, 75 (4 suppl), 2004. (impact factor 10.869)
  • Olckers A, Towers W, Wessels MN, Rheeder P and Schwarz P. Genotypic variation of specific SNPs in the Calpain 10 gene within a cohort of the Black South African population. American Journal of Human Genetics, 73 (5 suppl), p 521, 2003. (impact factor 10.869)
  • Alessandrini M, Van der Merwe A, Schutte C-M and Olckers A. Assessment of the translocation frequency between 4q and 10q in the South African FSHD population: a pilot study. American Journal of Human Genetics, 73 (5 suppl), p 270, 2003. (impact factor 10.869)
  • Mouton C, Semete B, Brand H and Olckers A. Causative malignant hyperthermia mutations excluded in the pathophysiology of South African clubfeet patients. American Journal of Human Genetics, 73 (5 suppl), p 556, 2003. (impact factor 10.869)
  • Smuts I, Van Brummelen AC, Wallace DC and Olckers A. Evaluation of the mitochondrial disease criteria scoring system in the South African population. American Journal of Human Genetics, 73 (5 suppl), p 462, 2003. (impact factor 10.869)
  • Van Brummelen AC, Smuts I, Wallace DC and Olckers A. Molecular screening of patients with mitochondrial disorders in the South African population. American Journal of Human Genetics, 73 (5 suppl), p 462, 2003.
  • Maree FF, Wedge BC, Prosser D, Gericke GS and Olckers A. Malignant Hyperthermia Susceptibility: Diagnosis in the South African Context, (abstract), American Journal of Human Genetics, 71 (4), p 544, 2002. (impact factor 10.869)
  • Van der Merwe A, Alessandrini M, Maree FF, Schutte C-M, Honey E, Frants RR, Vd Maarel SM, and Olckers A. The first compound heterozygote individual identified in the South African FSHD population, (abstract), American Journal of Human Genetics, 71 (4), p 523, 2002. (impact factor 10.869)
  • Alessandrini M, Vd Merwe A, Maree FF, Schutte C-M, Honey E, Frants RR, Vd Maarel SM and Olckers A. Molecular analysis suggests the first sporadic case of FSHD in the South African population (abstract), American Journal of Human Genetics, 71 (4), p 523, 2002. (impact factor 10.869)
  • Olckers A, Prosser D, Maree FF, Brown M, Wallace DC and Smuts I. Mitochondrial myopathies in the South African population: implications for diagnosis-lessons from the first four years, (abstract), American Journal of Human Genetics, 71 (4), p 466, 2002. (impact factor 10.869)
  • Olckers A, Prosser D, Wallace DC, Brown MD and Smuts I. Mitochondrial myopathies: a South African perspective (abstract), American Journal of Human Genetics, 69(4), p 490, 2001. (impact factor 10.869)
  • Vd Merwe A, Schutte CM, Vd Maarel SM, Alessandrini M, Honey E, Frants RR and Olckers A. DNA rearrangements at the D4Z4 locus in South African facioscapulohumeral muscular dystrophy, (abstract), American Journal of Human Genetics, 69(4), p 637, 2001. (impact factor 10.869)

Impact factors are listed above as they were at the time of publication.